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Understanding the PSA blood test

A guide for anyone concerned about prostate  cancer.

What is the PSA blood test?

The PSA test is a blood test that measures the amount of prostate specific antigen (PSA) in your blood. PSA is a protein produced by normal cells in the prostate and also by prostate cancer cells. It’s normal to have a small amount of PSA in your blood, and the amount rises as you get older. This is because your prostate gets bigger as you get older. A raised PSA level may suggest you have a problem with your prostate, but it might not be cancer.

Who can have a PSA blood test?

There is currently no screening programme for prostate cancer in the UK and you will not be invited for a PSA blood test by your GP. But you can have a PSA test at your GP surgery if you’re over 50 and you’ve thought carefully about the advantages and disadvantages (see page 23). If you have a higher risk of prostate cancer (see page 10), you may want to speak to your GP about having a PSA test from the age of 45. You may also be offered a PSA test if you have certain urinary symptoms (see page 8).

What can the PSA blood test tell me?

A raised PSA level can be a sign of a problem with your prostate. This could be:
  • an enlarged prostate
  • prostatitis
  • prostate cancer.
Other things can also cause your PSA level to rise (see page 15). If you have a raised PSA level, your GP might do other tests to find out what’s causing it, or they may refer you to see a specialist at the hospital.
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